Insulin dosages are somewhat reduced, injections are made more often. You should constantly alternate the injection sites of insulin.
Don't panic, it's most likely not an allergy. First of all, review the diet, remember that they started using household chemicals. Maria Nikolaevna, 54 years old, Perm.
Good afternoon. I was diagnosed with diabetes 4 years ago. Everything was fine, apart from my general hysteria about being sick. Now I'm taking Levemir, and lately I've been regularly dealing with allergies. A rash appears at the injection site, it itches a lot. I have never used this insulin before. What should I do? Good afternoon, Tatyana. You should contact your doctor and determine the true cause of the reactions. When was Levemir assigned to you? What was used before it and what changes appeared?
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I began to notice the manifestation of itching, but not only at the injection site, but throughout the body. Is it an allergy? And how can a diabetic live without insulin?
Hello, Maria Nikolaevna. You shouldn't worry. In any case, you need to consult a doctor and exclude the possibility of a violation.and in the work of any internal organs. The cause of itching all over the body can be not only insulin.
Have you used Pensulin before? This is pork insulin, which can be an allergen. The least allergenic human insulin. In its manufacture, sufficient purification is carried out, and it does not contain a protein cialis to humans, that is, there are alternative options for the appointment, be sure to consult a doctor. Allergy to insulin: types of reactions, symptoms, treatment, how to choose a drug.
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Bovine or porcine insulin is replaced with purified human insulin. If the treatment was ineffective, the patient is administered insulin along with hydrocortisone.
The least allergenic is human, then - bovine, and only after it - Cialis. Swelling, itching and pain may appear at the injection site. Less commonly, urticaria, anaphylaxis, and angioedema (swelling of the skin due to accumulation of fluid) appear.
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Cialis tadalafil reaction to insulin. Allergy to insulin occurs in patients with diabetes mellitus from 5% to 30% of cases. This is an overestimated susceptibility of immunity to insulin and the protein (protamine) and non-protein (zinc) components in the drug. Allergy manifests itself with the introduction of minimal doses of porcine, bovine or human insulin.
Allergies begin to appear within an hour (early symptoms) or after 5 hours (late), respectively, stop after 6 and 24 hours. Diagnosis occurs through anamnesis, tests and tests (the amount of histamine and immunoglobulins, etc.).
Allergies can be avoided or reduced by using modern purified drugs with DNA-recombinant human insulin, which must be administered according to cialis drug label. If this is not possible, then antihistamines will help.
Allergy to insulin and insulin resistance. Etiology. Insulin allergy and insulin resistance due to immune mechanisms are mediated by antibodies. The allergen may not be insulin, but protein (for example, protamine) and non-protein (for example, zinc) impurities that make up the drug. However, in most cases, tadalafil are caused by the insulin itself or its polymers, as evidenced by local allergic reactions to human insulin and systemic reactions to highly purified insulins.
Bovine, porcine, and human insulins are used to treat diabetes. Human insulin is less immunogenic than animal insulins, and porcine insulin is less immunogenic than bovine insulin. Bovine insulin differs from human insulin in two A-chain amino acid residues and one B-chain amino acid residue, while porcine insulin differs from human insulin in one B-chain amino acid residue.
The A-chains of human and porcine insulin are identical. Although human insulin is less immunogenic than porcine insulin, only human insulin is allergic. The degree of purification of insulin is determined by the content of proinsulin impurity in it. Insulin containing 10-25 µg/g of proinsulin was previously used, currently highly purified insulin containing less than 10 µg/g of proinsulin is used.
The transient nature of early local allergic reactions, as well as insulin resistance after desensitization to insulin, may be due to blocking IgG. Local allergic reactions developing 8-24 hours after insulin injection may be the result of cialis allergic reaction to insulin or zinc. Insulin resistance can be due to both immune and non-immune mechanisms. Non-immune mechanisms include obesity, ketoacidosis, endocrine disorders, infection. Insulin resistance due to immune mechanisms is very rare.
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It usually occurs during the first year of insulin treatment, develops over several weeks, and lasts from several days to several months. Sometimes insulin resistance occurs during desensitization to insulin.
Allergy to insulin can be manifested by local and systemic reactions. They occur in 5-10% of patients. Mild local reactions develop more often. Over the past few years, the prevalence of allergic reactions to insulin has decreased significantly.
Local allergic reactions (swelling, itching, pain) may be early or late. Early appear and disappear within 1 hour after injection, late - after a few hours (up to 24 hours). In some cases, the reaction is biphasic: its early manifestations last no more than 1 hour, then later, more persistent manifestations occur after 4-6 hours.
Sometimes a painful papule appears at the site of insulin injection, which persists for several days.
- Papules usually appear in the first 2 weeks of insulin treatment and disappear after a few weeks.
- Severe local allergic reactions, especially aggravated with each subsequent administration of insulin, often precede a systemic reaction.
- Systemic allergic reactions to insulin are relatively rare. Most often they are manifested by urticaria.
- Systemic allergic reactions usually occur when insulin therapy is resumed after a long break.